Fly to Rome and collect your hire car (based on group B car rental) and drive to Perugia. Stay 5 nights at the Sina Brufani, a 19th-century converted mansion which reflects the old world charm of Perugia and is located in the city's historic centre, within easy walking distance of its main attractions.
Full day at leisure to explore the celebrated National Gallery of Umbria, which contains 30 rooms of Italian artwork. (B)
Located 23km from Perugia is the town of Assisi, the spiritual home of Umbria. Visit the Basilica of San Francesco, which houses the greatest collection of medieval frescoes in Europe. (B)
Drive north along the shores of Lake Trasimeno to the town of Arezzo to explore the Basilica of San Francesco. (B)
Full day at leisure to explore the Renaissance architecture of Todi and the magnificent frescoes in the cathedral in Orvieto. (B)
Drive to Rome and drop off your hire car. Fly to your next destination. (B)